The Department of Biochemistry at the College of Science, Al-Mustaqbal University, continues to deliver practical lectures for fourth-year students as part of the Clinical Enzymology course. These lectures form an important part of the department’s efforts to strengthen students’ practical knowledge, develop their laboratory skills, and connect theoretical biochemical concepts with clinical applications used in medical laboratory investigations and diagnostic practice. As part of this ongoing educational programme, Asst. Lect. Hannadi Tahseen Muslim delivered a practical lecture on Aspartate Aminotransferase (AST), an important enzyme in clinical biochemistry due to its role in cellular biochemical reactions and its clinical significance in laboratory investigations used to assess liver health and certain other tissues. The lecture provided a scientific explanation of the biochemical nature and physiological function of AST. As a member of the aminotransferase enzyme family, AST catalyses the transfer of amino groups between amino acids and keto acids, contributing to amino acid metabolism and maintaining essential metabolic processes within the body. The discussion also highlighted the distribution of AST in several tissues, particularly the liver, heart, and skeletal muscles, explaining why changes in its activity may provide useful information in the assessment of different clinical conditions. A significant part of the lecture focused on the clinical importance of measuring AST activity in blood serum and understanding the possible causes of elevated enzyme levels. Students were introduced to the relationship between increased AST activity and cellular injury, particularly in tissues containing this enzyme. The lecture also emphasised its relevance to liver function assessment and explained that AST results should not be interpreted in isolation. Instead, they should be evaluated alongside other biochemical markers, particularly Alanine Aminotransferase (ALT), as well as additional laboratory findings and the patient’s clinical condition, to support a more accurate and scientifically grounded interpretation. Furthermore, the lecture highlighted the importance of understanding the principles underlying clinical enzyme measurements and recognising the diagnostic significance of biochemical laboratory results. This approach helps students develop a clearer understanding of how biochemical changes within the body are reflected in laboratory findings and how these findings contribute to the assessment and monitoring of various health conditions. The continuation of these practical lectures reflects the Department of Biochemistry’s commitment to improving the quality of academic education and strengthening the practical competencies of its students. By integrating biochemical theory with clinical laboratory applications, the department seeks to provide students with a solid scientific foundation in clinical enzymology and enhance their ability to understand laboratory investigations and interpret their results in accordance with established scientific principles. These educational activities also contribute to preparing graduates for future professional responsibilities in medical laboratories and scientific research. Al-Mustaqbal University – The First University in Iraq