Environmental sustainability in interior spaces is one of the most significant contemporary academic concerns in architecture and interior design. It plays an essential role in reducing the negative environmental impacts of buildings and improving quality of life. Sustainable interior design aims to balance aesthetic and functional requirements with environmental considerations through the efficient use of natural resources, reduced energy consumption, and the creation of healthy and comfortable indoor environments. This approach relies on selecting environmentally friendly materials that are recyclable and emit low levels of volatile organic compounds (VOCs), as well as maximizing natural lighting to reduce dependence on electrical energy. Thoughtful spatial planning also plays a significant role in promoting natural ventilation, improving air circulation, and regulating indoor humidity levels. These measures contribute to building efficiency and enhance the quality of the indoor environment. The benefits of sustainable interior design extend beyond environmental and economic considerations to include users’ physical and psychological well-being. Integrating natural elements into interior spaces through the principles of biophilic design, including the use of plants and natural materials such as wood and stone, can strengthen people’s connection with nature, promote comfort, and help reduce stress. Furthermore, appropriate lighting, effective ventilation, and safe interior materials contribute to healthier living and working environments that better meet human needs. Achieving sustainability in interior design requires a comprehensive assessment of the life cycle of materials, from extraction, manufacturing, and transportation to use, recycling, or disposal. Interior designers are responsible for selecting solutions that combine aesthetic quality with environmental efficiency while considering material durability, functional suitability, and long-term performance. The responsible use of resources and the integration of modern technologies can also minimize waste and improve the environmental performance of interior spaces. In conclusion, sustainable interior design represents an essential approach to addressing contemporary environmental challenges and advancing sustainable development in urban environments. Its effective implementation requires collaboration among designers, engineers, academic institutions, and relevant authorities, alongside greater awareness of environmentally responsible design practices. The future of interior design depends on its ability to develop innovative solutions that integrate creativity, aesthetics, health, and sustainability, creating better indoor environments for people while preserving natural resources.